1,4-Addition of TMSCCl3to Nitroalkenes: Efficient Reaction Conditions and Mechanistic Understanding
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چکیده
منابع مشابه
1,4-Addition of TMSCCl3 to Nitroalkenes: Efficient Reaction Conditions and Mechanistic Understanding
Improved synthetic conditions allow preparation of TMSCCl3 in good yield (70%) and excellent purity. Compounds of the type NBu4X [X=Ph3SiF2 (TBAT), F (tetrabutylammonium fluoride, TBAF), OAc, Cl and Br] act as catalytic promoters for 1,4-additions to a range of cyclic and acyclic nitroalkenes, in THF at 0-25 °C, typically in moderate to excellent yields (37-95%). TBAT is the most effective prom...
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ژورنال
عنوان ژورنال: Chemistry - A European Journal
سال: 2014
ISSN: 0947-6539
DOI: 10.1002/chem.201402394